Officials with American Airlines will try to convince a bankruptcy judge that labor agreements must be broken for the carrier to survive.
Leaders of the Fort Worth-based airline on Monday will be at a federal courthouse in New York to open what could be a two-month hearing.
Parent company AMR seeks to void its contracts with pilots, flight attendants and ground workers and impose its own terms.
The airline lost more than $10 billion in the decade leading up to its declaration of bankruptcy last November.